Transcription activator like effector nucleases (TALENs) is a new and powerful technique in genetic engineering that can delete deleterious genes or add beneficial genes to organisms. It is being widely studied to improve crops and livestock, and is also being investigated clinically. Comparing the details of how both TALENs and its competitor, CRISPR-Cas9, function, reveals the potential advantages of TALENs. The growing literature, besides covering the scientific and technical aspects of TALENs, also includes pertinent information on regulatory aspects and the public’s perception and acceptance of TALENs.
Philip Barnett. Transcription Activator Like Effector Nucleases (TALENs): A New, Important, and Versatile Gene Editing Technique with a Growing Literature. Science & Technology Libraries. Volume 37 Issue 1 pages 100-112. Published online: 13 Dec 2017.