Machine Learning (ML), including Deep Learning (DL), systems, i.e., those with ML capabilities, are pervasive in today’s data-driven society. Such systems are complex; they are comprised of ML models and many subsystems that support learning processes. As with other complex systems, ML systems are prone to classic technical debt issues, especially when such systems are long-lived, but they also exhibit debt specific to these systems. Unfortunately, there is a gap in knowledge of how ML systems evolve and are maintained. In this paper, we fill this gap by studying refactorings, i.e., source-to-source semantics-preserving program transformations, performed in real-world, open-source software, and the technical debt issues they alleviate. We analyzed 26 projects, consisting of 4.2 MLOC, along with 327 manually examined code patches. The results indicate that developers refactor these systems for a variety of reasons, both specific and tangential to ML, some refactorings correspond to established technical debt categories, while others do not, and code duplication is a major cross-cutting theme that mainly involved ML configuration and model code, which was also the most refactored. We also introduce 14 and 7 new ML-specific refactorings and technical debt categories, respectively, and propose several recommendations, best practices, and anti-patterns. The results can potentially assist practitioners, tool developers, and educators in facilitating long-term ML system usefulness.