Date of Award
Spring 5-1-2026
Document Type
Thesis
Degree Name
Master of Arts (MA)
Department
Psychology
First Advisor
Peter Serrano
Second Advisor
Michael J. Lewis
Academic Program Adviser
Sandeep Prasada
Abstract
Prophylactic brivaracetam (BRV) was evaluated in a rat TBI model for effects on behavior and serum tau. BRV reduced anxiety-like behavior with optimal dose-dependent effects at 2.1mg/kg, but did not affect working memory. Serum tau was detectable early post-injury, supporting its use as a biomarker.
Recommended Citation
Dumic, Sofia, "Neuroprotective Effects of Prophylactic Brivaracetam on Memory and Anxiety Following Traumatic Brain Injury" (2026). CUNY Academic Works.
https://academicworks.cuny.edu/hc_sas_etds/1463
Included in
Animal Studies Commons, Behavior and Behavior Mechanisms Commons, Comparative Psychology Commons
