Date of Award

Spring 5-2-2019

Document Type

Thesis

Degree Name

Master of Arts (MA)

Department

Biological Sciences

First Advisor

Paul Feinstein

Second Advisor

Patricia Rockwell

Academic Program Adviser

Olorunseun Ogunwobi

Abstract

How expression of odorant receptors affects the maturation of olfactory sensory neurons (OSNs) is not known. In a time course experiment, we show that wild type OSNs mature significantly more than those expressing Neomorphic mutant receptors. We conclude that functional receptors are critical to the differentiation and survival of OSNs.

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