Date of Award

Spring 5-15-2020

Document Type

Thesis

Degree Name

Master of Arts (MA)

Departments/Programs

Biological Sciences

First Advisor

Carmen Melendez-Vasquez

Second Advisor

Patrizia Casaccia

Academic Program Adviser

Diego Loayza

Abstract

Non-Muscle Myosin II (NMII) is a mechanosensitive motor protein implicated in oligodendrocyte (OL) development. The inhibition of NMII is known to promote OL development and maturation. This project found that NMII inhibition does not affect oligodendrocyte development by altering their epigenetic profile.

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