Publications and Research
Document Type
Article
Publication Date
3-25-2013
Abstract
In 2001, Friedman et al. conjectured the existence of a “firewall effect” in which individuals who are infected with HIV, but remain in a state of low infectiousness, serve to prevent the virus from spreading. To evaluate this historical conjecture, we develop a new graph-theoreticmeasure that quantifies the extent towhich Friedman’s firewall hypothesis (FH) holds in a risk network.We compute this new measure across simulated trajectories of a stochastic discrete dynamical system that models a social network of 25,000 individuals engaging in risk acts over a period of 15 years. The model’s parameters are based on analyses of data collected in prior studies of the real-world risk networks of people who inject drugs (PWID) in New York City. Analysis of system trajectories reveals the structural mechanisms by which individuals with mature HIV infections tend to partition the network into homogeneous clusters (with respect to infection status) and how uninfected clusters remain relatively stable (with respect to infection status) over long stretches of time. We confirm the spontaneous emergence of network firewalls in the system and reveal their structural role in the nonspreading of HIV.
Comments
This article was originally published in Discrete Dynamics in Nature and Society, available at http://dx.doi.org/10.1155/2013/720818.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.