The application of electric cell-substrate impedance sensing (ECIS) biosensors

Authors

Xudong Zhang, CUNY Graduate CenterFollow
Sunghoon Jang, CUNY New York City College of TechnologyFollow

Document Type

Article

Publication Date

11-12-2018

Abstract

Electric cell-substrate impedance sensing (ECIS) is a label-free and non-invasive technique for analyzing the activities and morphologies of cells. The ECIS sensors are able to measure the impedance spectroscopy of cells attaching on the sensor substrates. The cell activities and morphologies influence the measure impedance directly. Traditional toxicity analysis has complicated processes compared to biosensor-based analysis. In this study, the toxicity analysis was performed with biosensor based on ECIS technique. The experimental results show that the ECIS sensor is able to quickly distinguish the toxic and non-toxic substance.

Comments

This work was originally published in Biosensors and Bioelectronics, available at DOI: 10.15406/ijbsbe.2018.04.00136. It is distributed under CC BY NC Creative Commons 4.0 license.