Periampullary cancer is a complex disease of heterogenous origin. This is cancer arising within 2 cm of the papilla of Vater and includes pancreatic, ampullary, biliary and duodenal cancers. Duodenal cancer has the highest estimated 5-year survival (49%), followed by ampullary cancer (45%), distal bile duct cancer (27%), and pancreatic cancer (18%). (Ray-Offor, 2019, ¶ 1)
Soloviova, Tetiana, "Case presentation on periampullary cancer and ampullectomy" (2020). CUNY Academic Works.