Dissertations, Theses, and Capstone Projects
Date of Degree
5-2018
Document Type
Dissertation
Degree Name
Ph.D.
Program
Biology
Advisor
Anuradha Janakiraman
Committee Members
David Jeruzalmi
Shireen Saleque
Andrew Darwin
Lars Dietrich
Anuradha Janakiraman
Subject Categories
Bacteriology | Biochemistry | Biology | Biophysics | Cell Biology | Cellular and Molecular Physiology | Genetics | Microbial Physiology | Molecular Biology | Molecular Genetics | Organismal Biological Physiology | Structural Biology
Keywords
cytokinesis, division, FtsZ, E. coli, microbiology, genetics
Abstract
Escherichia coli is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand E. coli undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how E. coli cell division is regulated.
Recommended Citation
Buczek, Monika S., "Regulation of the Tubulin Homolog FtsZ in Escherichia coli" (2018). CUNY Academic Works.
https://academicworks.cuny.edu/gc_etds/2738
Included in
Bacteriology Commons, Biochemistry Commons, Biology Commons, Biophysics Commons, Cell Biology Commons, Cellular and Molecular Physiology Commons, Genetics Commons, Microbial Physiology Commons, Molecular Biology Commons, Molecular Genetics Commons, Organismal Biological Physiology Commons, Structural Biology Commons