Publications and Research

Document Type

Article

Publication Date

10-12-2016

Abstract

Non-randomized studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomized Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that did not use randomization to allocate units (individuals or clusters of individuals) to comparison groups. The tool will be particularly useful to those undertaking systematic reviews that include non-randomized studies.

Comments

This article was originally published in BMJ, available at http://dx.doi.org/10.1136/bmj.i4919.

This article is an open access article published under a Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license.

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