Diﬀuse optical imaging (DOI) for detecting and locating targets in a highly scattering turbid medium is treated as a blind source separation (BSS) problem. Three matrix decomposition methods, independent component analysis (ICA), principal component analysis (PCA), and nonnegative matrix factorization (NMF) were used to study the DOI problem. The eﬃcacy of resulting approaches was evaluated and compared using simulated and experimental data. Samples used in the experiments included Intralipid-10% or Intralipid-20% suspension in water as the medium with absorptive or scattering targets embedded.
Wu, Binlin; Alrubaiee, M.; Cai, W.; Xu, M.; and Gayen, S. K., "Diffuse Optical Imaging Using Decomposition Methods" (2012). CUNY Academic Works.