The Community Loss Index ðCLIÞ, a new social indicator, focuses on the understudied role of place as a source of stress and an aggregator of individual experiences. Building on the relationship between loss and stress, the index attempts to capture collective loss, defined as the chronic exposure by neighborhood residents to multiple resource losses at the same time. Using maps, the article analyzes the spatial distribution of six types of loss in New York City and the characteristics of people who live in high- and low-loss neighborhoods. Regionalization reveals a neighborhood-based concentration of loss, patterns of loss that are both widespread and variable by location, and that a group’s vulnerability to the adverse effects of community loss depends on where the group lives. The CLI provides a place-based context for investigating neighborhood-based collective loss and allows community members and public officials to fine-tune interventions based on actual community needs.