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Objective We performed a systematic review, metaanalysis and meta-regression to determine if dietary protein supplementation augments resistance exercise training (RET)-induced gains in muscle mass and strength.

Data sources A systematic search of Medline, Embase, CINAHL and SportDiscus.

Eligibility criteria Only randomised controlled trials with RET ≥6 weeks in duration and dietary protein supplementation.

Design Random-effects meta-analyses and metaregressions with four a priori determined covariates. Twophase break point analysis was used to determine the relationship between total protein intake and changes in fat-free mass (FFM).

ResultsData from 49 studies with 1863 participants showed that dietary protein supplementation significantly (all p

Summary/conclusion Dietary protein supplementation significantly enhanced changes in muscle strength and size during prolonged RET in healthy adults. Increasing age reduces and training experience increases the efficacy of protein supplementation during RET. With protein supplementation, protein intakes at amounts greater than ~1.6 g/kg/day do not further contribute RET-induced gains in FFM.


This article was originally published in the British Journal of Sports Medicine, available at http:// dx. doi. org/ 10. 1136/ bjsports- 2017- 097608.

This is an open access article distributed under the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) License.



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