A spray Passive Downdraft Evaporative Cooling (PDEC) system achieves great savings for space cooling and improves indoor environmental quality by supplying a large amount of fresh outdoor air. As previous studies heavily focused on the energy saving capability of a spray PDEC system due to lack of methods for a detailed analysis, the influence of cool humid supply air from a spray PDEC system in a space in buildings has not been comprehensively studied. This study is intended to evaluate the competence of a spray PDEC system as a primary cooling system in typical spaces in a primary school building by developing a method using building energy simulation tool. It runs one-day simulations in a hot dry climate and a warm moderate climate in order to distinctly examine the benefits and the areas that should be advanced. It analyses how a spray PDEC system responds to the space cooling loads and spaces conditioned by the system thermally behave. The results of the simulations affirm that a spray PDEC system is capable of conditioning building spaces in the two climates, indicating some areas to be improved.