Date of Award
Spring 5-12-2020
Document Type
Thesis
Degree Name
Master of Arts (MA)
Department
Biological Sciences
First Advisor
Patricia Rockwell
Second Advisor
Maria Figueiredo-Pereira
Academic Program Adviser
Patricia Rockwell
Abstract
Currently, Alzheimer’s disease (AD) has no cure. Using a rat AD model, we identified aberrantly expressed proteins during pre-pathology as potential biomarkers. The expression of certain biomarkers was reversed by diazoxide, a repurposed hypertension drug. These results suggest that drug repurposing at an early stage of AD has therapeutic potential.
Recommended Citation
Islam, Rangon, "Expression Analyses of Hippocampal and Cortical Proteins in a Rat Model for Alzheimer’s Disease" (2020). CUNY Academic Works.
https://academicworks.cuny.edu/hc_sas_etds/583
Included in
Biotechnology Commons, Cell Biology Commons, Molecular and Cellular Neuroscience Commons