Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture

Authors

Gary Xie, University of Florida
Carol A. Bonner, Los Alamos National Laboratory
Roy A. Jensen, CUNY City College

Document Type

Article

Publication Date

August 2002

Abstract

The factors that accommodate the transition of different chlamydial species to the persistent state of pathogenesis include marked differences in the strategied deplyed to obtain tryptophan from host resources. Chlamydia psittaci appears to have a novel mechanism for intercepting an early intermediate of tryptophan catabolism and recycling it back to tryptophan.

Comments

This work was originally published in Genome Biology, available at doi: 10.1186/gb-2002-3-9-research0051