Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis

Authors

Dibash K. Das, CUNY Hunter CollegeFollow
Thahmina Ali, CUNY Hunter CollegeFollow
Konstantinos Krampis, CUNY Hunter CollegeFollow
Olorunseun O. Ogunwobi, CUNY Hunter CollegeFollow

Document Type

Article

Publication Date

2-3-2017

Abstract

Prostate cancer is the second most commonly diagnosed male cancer in the world. The molecular mechanisms underlying its development and progression are still unclear. Here we show analysis of a prostate cancer RNA-sequencing dataset that was originally generated by Ren et al. [3] from the prostate tumor and adjacent normal tissues of 14 patients. The data presented here was analyzed using our RNA-sequencing bioinformatics analysis pipeline implemented on the bioinformatics web platform, Galaxy. The relative expression of fibronectin (FN1) and the androgen receptor (AR) were calculated in fragments per kilobase of transcript per million mapped reads, and represented in FPKM unit. A subanalysis is also shown for data from three patients, that includes the relative expression of FN1 and AR and their fold change. For interpretation and discussion, please refer to the article, “miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin” [1] by Das et al.

Comments

This article originally appeared in Data in Brief, available at http://dx.doi.org/10.1016/j.dib.2017.01.016

This is an open access article under the CCBY license (http://creativecommons.org/licenses/by/4.0/).