Date of Award

Fall 12-21-2016

Document Type

Thesis

Degree Name

Master of Arts (MA)

Department

Biological Sciences

First Advisor

Dr. Thomas Schmidt-Glenewinkel

Second Advisor

Dr. Jeremy Coplan

Academic Program Adviser

Dr. Olorunseun Ogunwobi

Abstract

Early-Life Stress (ELS) is associated with vulnerability to mood disorder, but it’s not well understood how ELS contributes to deficits in cognitive function. Atypical PKMzeta is critical for LTP maintenance and memory. The current study aims to characterize the ELS phenotype with respect to this key marker of hippocampal LTP.

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