Date of Award
Master of Arts (MA)
Academic Program Adviser
Currently, Alzheimer’s disease (AD) has no cure. Using a rat AD model, we identified aberrantly expressed proteins during pre-pathology as potential biomarkers. The expression of certain biomarkers was reversed by diazoxide, a repurposed hypertension drug. These results suggest that drug repurposing at an early stage of AD has therapeutic potential.
Islam, Rangon, "Expression Analyses of Hippocampal and Cortical Proteins in a Rat Model for Alzheimer’s Disease" (2020). CUNY Academic Works.