Date of Award

Spring 5-15-2020

Document Type

Thesis

Degree Name

Master of Arts (MA)

Departments/Programs

Biological Sciences

First Advisor

Olorunseun Ogunwobi

Second Advisor

Jill Bargonetti

Abstract

Claudin low triple negative breast cancer (TNBC) has the worst clinical outcomes in comparison to other breast cancer subtypes. The underlying molecular mechanisms associated with the aberrant expression of claudins are not well understood. The transcript from PVT1 exon 9 is a regulator of claudin expression, and migration, in TNBC.

Included in

Biology Commons

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