Date of Award

Fall 12-9-2024

Document Type

Thesis

Degree Name

Master of Science (MS)

Department/Program

Forensic Science

Language

English

First Advisor or Mentor

Ana Pego

Second Reader

Marta Concheiro-Guisan

Third Advisor

Michelle Carlin

Abstract

In recent years, per- and polyfluoroalkyl substances (PFAS) have emerged as a critical focus in environmental and public health research due to their persistent nature and widespread use in products ranging from non-stick cookware to firefighting foams. These "forever chemicals" resist degradation, posing significant ecological and human health risks. While extensive studies have explored PFAS in environmental matrices, research into their presence in human hair remains limited, with only a handful of studies addressing this biomarker's potential. This thesis aims to develop a robust analytical method for detecting PFAS in human hair, leveraging its unique properties to provide a long-term record of chemical exposure. Hair analysis offers a non-invasive, stable, and comprehensive approach to monitoring PFAS, which can establish exposure timelines and baseline population levels. This methodology could identify high risk groups, including professionals in fire safety, petrochemical, military, and aviation industries, and communities near contaminated sites. The findings of this research will contribute to understanding PFAS exposure disparities across different demographic groups, emphasizing the need for environmental justice. By identifying individuals at heightened risk, the study aims to support targeted interventions and policy development to protect vulnerable populations from PFAS contamination.

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