The Synthesis of Angucyclines using an Intramolecular Bradsher Cycloaddition

Authors

Abdullah Allaoa, CUNY New York City College of TechnologyFollow
Tony E. Nicolas, CUNY New York City College of Technology

Document Type

Poster

Publication Date

5-4-2016

Abstract

The Angucyclines are natural products which possess a broad spectrum of biological properties. Of particular interest are the natural products which contain the cis-hydroxyl motif at the AB ring junction. Their synthesis is particularly challenging. Our model study has resulted in the synthesis of a model of the angucyclines with the required cis-hydroxyl features. The present work will apply the previously developed chemistry to an intramolecular version which will lead to the synthesis of the ABC ring system

Comments

This poster was presented at the 24th Semi-Annual Honors and Undergraduate Research Scholars Poster Presentation at New York City College of Technology, May 4, 2016.

Mentor: Prof. T. Nicholas, Chemistry