Date of Award
Fall 1-2-2026
Document Type
Thesis
Degree Name
Master of Arts (MA)
Department
Chemistry
First Advisor
Hiroshi Matsui
Second Advisor
Dhiman S. Pal
Academic Program Adviser
Yujia Xu
Abstract
Peptide nano-assemblies can regulate cellular pathways in a structure-dependent manner. Here, we show that the enzyme-responsive peptide NapFFK(NBD)Yp forms distinct nanoscale assemblies at different concentrations, triggering differential ER stress and extracellular vesicle release in MDA-MB231 cells. These results highlight the importance of supramolecular organization in peptide–cell interactions.
Recommended Citation
Rozmetova, Malika, "Structural Characterization of Peptide Nanoaggregates at Varying Concentrations and Their Impact on Cellular Responses" (2026). CUNY Academic Works.
https://academicworks.cuny.edu/hc_sas_etds/1442
