Date of Award
Winter 1-14-2021
Document Type
Thesis
Degree Name
Master of Arts (MA)
Department
Chemistry
First Advisor
Yujia Xu
Second Advisor
Nancy Greenbaum
Academic Program Adviser
Yujia Xu
Abstract
This paper attempts to design collagen mimetic peptides where the triple-helical region mimics that of human Type I Collagen. With consideration for chain selection and chain register, we utilize the NC2 domain of heterotrimeric Type IX Collagen as a nucleation domain for triple-helix folding.
Recommended Citation
Tan, Sally, "Design of Fibril Forming Collagen Mimetic Peptides: Heterotrimers and Nucleation Domains" (2021). CUNY Academic Works.
https://academicworks.cuny.edu/hc_sas_etds/835
Included in
Biochemistry Commons, Other Biochemistry, Biophysics, and Structural Biology Commons, Structural Biology Commons