Publications and Research

Document Type

Article

Publication Date

5-22-2024

Abstract

In Tajikistan, the Allium genus is notably prolific, with over 80 species documented, and new species continually being identified in the mountainous regions. The Gorno- Badakhshan Autonomous Region (GBAO) of Tajikistan, within the Pamir Mountains, is significant for its 31 distinct Allium species, including endemics like A. afghanicum Wendelbo and A. schugnanicum Vved. The distribution of these species is often geographically restricted, and their biological activities, especially their antimicrobial properties, remain largely unexplored, presenting significant opportunities for future phytochemical and pharmacological research. This scholarly inquiry is aimed at contributing substantially to the academic discourse on the therapeutic capacities of Allium species, focusing particularly on their polyphenolic profiles and resultant bioactive functionalities. Our investigation revealed distinct correlations between antioxidant activity and antibacterial efficacy across different parts of selected Allium species. Notably, antioxidant activities in A. altaicum leaves and A. elatum flowers exhibited positive correlations with antibacterial effects against Staphylococcus aureus. Additionally, the bulbs of A. suworowii demonstrated a moderate positive correlation in this regard. Conversely, negative correlations were identified for P. aeruginosa in the bulbs of A. oschaninii, A. schoenoprasum, and A. sativum. Particularly striking was the strong negative correlation between antioxidant activity and the anti - E. coli effect observed in A. hymenorhizum flowers. Furthermore, the leaves of A. oschaninii and A. schugnanicum exhibited contrasting correlations with antibacterial effects, underscoring the complex interplay between antioxidant activity and antibacterial efficacy within these species. These findings suggest that the relationship between antioxidant activity and antibacterial effects is not uniform across all Allium species or bacterial strains. The observed variability implies that factors beyond antioxidant activity per se may influence the antibacterial potential of these plant extracts. Key words: Allium species, polyphenol content, antioxidant activity, antimicrobial and anfungal properties, test microorganisms

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This work is distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

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