Date of Award
Fall 12-2024
Document Type
Thesis
Degree Name
Master of Science (MS)
Department/Program
Forensic Science
Language
English
First Advisor or Mentor
Marta Concheiro-Guisán
Second Reader
Ana Pego
Third Advisor
Michelle Carlin
Abstract
Tryptamines are psychedelic drugs that cause an individual to undergo hallucinogenic effects such as the distortion of time and space and loss of reality. Psilocybin, a classic hallucinogenic, is a Schedule I drug that has recently been given more leeway regarding research for therapeutic use. With the rise of psychedelics comes more tryptamine-designer drugs on the market and their potential misuse and diversion. This study aimed to develop and validate a method for the determination of six tryptamines and metabolites— psilocin, psilocybin, psilacetin, 4-propionoxy-N,N-dimethyltryptamine, 4-methyl carbonate-N,N-dipropyltryptamine, and 4-hydroxy-N, N-dipropyltryptamine-in plasma by liquid chromatography-tandem mass spectrometry.
Recommended Citation
Schoffner, Malik X., "Development and Validation of an Analytical Method for the Determination of Tryptamines in Plasma by Liquid Chromatography-Tandem Mass Spectrometry" (2024). CUNY Academic Works.
https://academicworks.cuny.edu/jj_etds/336
