Date of Award
Dr. Zaghloul Ahmed
Trans-spinal direct current stimulation (tsDCS) is a non-invasive powerful tool demonstrated to positively affect behavior and motor function. tsDCS is a neuromodulatory technique capable of altering spinal and cortical excitability and even regain motor function after complete motor paralysis (Cortes et at, 2017). tsDCS causes immediate and long-term effects in spinal excitability (Ahmed, 2011, 2013; Ahmed and Wieraszko, 2012; Cogiamanian et al., 2011, 2012). Studies have been conducted on both healthy and injured subjects. The ultimate goal is to ameliorate the devastating effects of Spinal Cord Injury. Though researchers have been successful in improving motor function, the molecular basis of the recovery still remains unknown. Our objective for this study was to investigate the effect of tsDCS on transporter protein NKCC1 for both healthy and injured animals.
Weliwaththage, Pasindu, "Investigating the Effects of Trans-Spinal Direct Current Stimulation on The Expression of NKCC1 In Mice" (2018). CUNY Academic Works.